ALK positive - research and fundraise
Lung cancer charity

Research Projects & Partners

Lung Cancer Research Foundation

2024 LCRF Research Grant on Early Detection and Pre-Neoplasia in Lung Cancer

Peggy Hsu, MD, PhD
University of Michigan

RESEARCH PROJECT:
Understanding the origin of ALK-driven lung cancer

SUMMARY:
ALK-positive lung cancer, often affecting non-smokers and diagnosed at advanced stages, has unclear origins. This research aims to uncover the earliest events driving ALK-driven lung cancer using advanced single-cell technologies. By studying patient samples, lung organoids, and mouse models, the team will map how ALK activation leads to tumor initiation. The findings could reveal novel molecular features, enhance our understanding of cancer cell plasticity, and pave the way for earlier detection and prevention strategies, improving survival rates for ALK+ lung cancer patients.

Thank you to Research ALKay+ve UK for fully funding a research grant that will have a profound impact on the ALK+ hashtag#LungCancer community in memory of Kay Murgatroyd.

“We made this gift to LCRF because of the innovative proposal and outstanding team working for this organization. Kay’s profound impact shall forever be known; marking her name in this project reinforces her commitment to be 'forever fundraising for ALK+ lung cancer' - which we will continue to do.”

Ewan Murgatroyd

Find out more:

Download details of the Research Project funded by ALKay+ve HERE

Read more about the work of the Lung Cancer Research Foundation by visiting their website HERE

Follow the Research Project progress HERE